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Blood-Brain Barrier in Drug Discovery: Optimizing Brain Exposure of CNS Drugs and Minimizing Brain Side Effects for Peripheral Drugs 1st Edition

Product code : 1504682375

by Li Di (Editor), Edward H. Kerns (Editor)

$12.00
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    Blood-Brain Barrier in Drug Discovery: Optimizing Brain Exposure of CNS Drugs and Minimizing Brain Side Effects for Peripheral Drugs 1st Edition 
    by Li Di (Editor), Edward H. Kerns (Editor).
    Focused on central nervous system (CNS) drug discovery efforts, this book educates drug researchers about the blood-brain barrier (BBB) so they can affect important improvements in one of the most significant – and most challenging – areas of drug discovery.
    • Written by world experts to provide practical solutions to increase brain penetration or minimize CNS side-effects
    • Reviews state-of-the-art in silico, in vitro, and in vivo tools to assess brain penetration and advanced CNS drug delivery strategies
    • Covers BBB physiology, medicinal chemistry design principles, free drug hypothesis for the BBB, and transport mechanisms including passive diffusion, uptake/efflux transporters, and receptor-mediated processes...

    Product details
    • Print Length : 616 pages
    • Publisher: Wiley Education / Medical; 1 edition (2015)
    • Language: English.
      Type : PDF 
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