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Breast Cancer: Diagnostic Imaging and Therapeutic Guidance 1st Edition

Product code : 1604298528

by Uwe Fischer (Author), Friedemann Baum (Author), Susanne Luftner-Nagel (Author)

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    Breast Cancer: Diagnostic Imaging and Therapeutic Guidance 1st Edition 
    by Uwe Fischer (Author), Friedemann Baum (Author), Susanne Luftner-Nagel (Author) .
    Breast Cancer: Diagnostic Imaging and Therapeutic Guidance
    Title Page
    Copyright
    Contents
    Preface
    Contributors
    Abbreviations
    Part 1: Anatomy, Physiology, and Pathology of the Breast
    1 Development, Anatomy, and Physiology of the Mammary Gland
    1.1 Development
    1.2 Anatomy
    1.3 Physiology
    Bibliography
    2 Tumor Formation
    2.1 Mutation, Carcinogenesis, and Angiogenesis
    2.2 Risk Factors
    2.3 Genetic Risk Factors
    2.4 Prevention
    2.4.1 Primary Prevention
    2.4.2 Secondary Prevention
    2.4.3 Tertiary Prevention
    2.5 Epidemiology, Incidence, and Mortality
    Bibliography
    3 Pathology of Benign and Malignant Changes in the Breast
    3.1 Benign Changes
    3.1.1 Histological Principles
    3.1.2 Nonneoplastic, Nonproliferative Diseases of the Breast
    3.1.3 Benign Tumor-Forming Diseases
    3.2 Malignant Changes in the Breast
    3.2.1 Classification of Malignant Breast Tumors (WHO Classification, B-Categories)
    3.2.2 Prognostic and Predictive Factors
    3.2.3 Papillary Lesions
    3.2.4 Ductal Carcinoma In Situ
    3.2.5 Microinvasive and Invasive Breast Carcinoma
    3.2.6 Tumors of the Nipple
    3.2.7 Malignant Mesenchymal Tumors and Lymphomas of the Breast
    3.2.8 Metastatic Tumors
    3.3 Acknowledgments
    Bibliography
    Part 2: Breast Diagnostics
    4 Nonimaging Diagnostics
    4.1 History
    4.2 Informed Consent
    4.3 Self-Examination
    4.4 Inspection
    4.5 Palpation
    Bibliography
    5 Mammography
    5.1 Technique and Methods
    5.1.1 Principles of X-ray Mammography
    5.1.2 Components of a Mammography System
    5.1.3 Exposure Parameters
    5.1.4 Image Quality
    5.1.5 Analog Mammography
    5.1.6 Digital Mammography
    5.1.7 Radiation Exposure
    5.2 Parameters and Positioning
    5.2.1 Standard Projections
    5.2.2 Supplementary Views
    5.2.3 Galactography
    5.2.4 Mammography of the Male Breast
    5.2.5 Quality Assurance in Parameters and Positioning
    5.3 Interpretation of Mammograms
    5.3.1 Terminology
    5.3.2 Tissue Density in a Mammogram According to the ACR BI-RADS Atlas
    5.3.3 Interpretation Criteria
    5.3.4 BI-RADS Classification of Mammography
    5.3.5 Normal Findings in the Mammogram
    Bibliography
    6 Breast Ultrasonography
    6.1 Technique and Methods
    6.1.1 Basic Principles
    6.1.2 Device Adjustments
    6.1.3 Examination Technique
    6.1.4 Ultrasound Techniques
    6.1.5 Quality Assurance
    6.2 Evaluation
    6.2.1 Terminology
    6.2.2 Tissue Type in Sonography
    6.2.3 Evaluation Criteria
    6.2.4 BI-RADS Classification of Breast Ultrasonography
    6.2.5 Normal Findings in Sonography
    Bibliography
    7 Magnetic Resonance Imaging of the Breast
    7.1 Technique and Methods
    7.1.1 Basic Principles
    7.1.2 Tumor Detection
    7.1.3 Equipment
    7.1.4 Timing of the Examination
    7.1.5 Patient Positioning
    7.1.6 Measurement Parameters
    7.1.7 Image Postprocessing
    7.1.8 Implant Evaluation
    7.1.9 Nonestablished Examination Techniques
    7.2 Evaluation
    7.2.1 Terminology
    7.2.2 Perfusion Pattern
    7.2.3 Findings in the T1-Weighted Precontrast Image
    7.2.4 Findings in the T2-Weighted Image
    7.2.5 Findings in the T1-Weighted Contrast-Enhanced Image
    7.2.6 Evaluation Criteria
    7.2.7 BI-RADS Classification of MRI of the Breast
    7.2.8 Normal Findings in MRI of the Breast
    Bibliography
    8 Imaging of Breast Lesions
    8.1 Benign Findings
    8.1.1 Cysts
    8.1.2 Inflamed Cysts
    8.1.3 Complex Cysts
    8.1.4 Myxoid Fibroadenoma
    8.1.5 Fibrotic Fibroadenoma
    8.1.6 Adenoma
    8.1.7 Hamartoma
    8.1.8 Lipoma
    8.1.9 Mammary Fibrosis
    8.1.10 Adenosis of the Breast
    8.1.11 Fibrocystic Condition of the Breast
    8.1.12 Adenomyoepithelioma
    8.1.13 Acute Nonpuerperal Mastitis
    8.1.14 Chronic Nonpuerperal Mastitis
    8.1.15 Intramammary Lymph Nodes
    8.1.16 Pseudoangiomatous Stromal Hyperplasia
    8.1.17 Seroma
    8.1.18 Hematoma
    8.1.19 Fat Necrosis (Oil Cyst)
    8.1.20 Abscess
    8.1.21 Postoperative Scars
    8.2 Findings with Ambiguous Biological Potential
    8.2.1 Papillomas
    8.2.2 Radial Scars
    8.2.3 Atypical Ductal Hyperplasia
    8.2.4 Phyllodes Tumors
    8.2.5 Cysts with Intracystic Proliferation
    8.2.6 Lobular Intraepithelial Neoplasia
    8.3 Intraductal Carcinoma
    8.3.1 Ductal Carcinoma In Situ (Low Grade)
    8.3.2 Ductal Carcinoma In Situ (Intermediate Type)
    8.3.3 Ductal Carcinoma In Situ (High Grade)
    8.4 Invasive Tumors
    8.4.1 Invasive Ductal Carcinoma
    8.4.2 Invasive Lobular Carcinoma
    8.4.3 Tubular Carcinoma
    8.4.4 Medullary Carcinoma
    8.4.5 Mucinous Carcinoma
    8.4.6 Invasive Papillary Carcinoma
    8.4.7 Sarcomas
    8.4.8 Triple-Negative Carcinoma
    8.4.9 Paget’s Disease of the Nipple
    8.4.10 Inflammatory Carcinoma
    8.4.11 Systemic Diseases Involving the Breast
    9 Breast Intervention
    9.1 Biopsy
    9.1.1 Objective of Percutaneous Tissue Sampling
    9.1.2 Percutaneous Tissue Sampling Equipment and Implementation
    9.1.3 Interventional Imaging
    9.1.4 Classification of Findings
    9.1.5 Tumor Seeding and Mechanical Tumor Induction
    9.1.6 Quality Assurance
    9.2 Localization
    9.2.1 Objective of Pretherapeutic Localization
    9.2.2 Equipment and Implementation
    9.2.3 Quality Assurance
    Bibliography
    Part 3: Prevention and Therapy of Breast Cancer
    10 Examination Concepts
    10.1 Prevention
    10.2 Early Breast Cancer Detection (Secondary Prevention)
    10.2.1 Mammography Screening
    10.2.2 Individualized Examination Concepts
    10.2.3 Early Detection inWomen with a High-Risk Profile
    10.2.4 Future Concepts of Early Breast Cancer Detection
    10.3 Diagnostic Work-up
    10.4 Pretherapeutic Local Staging
    10.5 Pretherapeutic Peripheral Staging
    10.6 Follow-up Care
    10.7 Implant Evaluation
    10.8 Evaluation of the Male Breast
    Bibliography
    11 Surgical Treatment of Breast Carcinoma
    11.1 Significance of Surgery in the Context of Multimodal Treatment of Breast Carcinoma
    11.2 Types of Breast Carcinoma
    11.2.1 Lesions of Uncertain Biological Potential (B3 Lesions)
    11.2.2 Preinvasive Carcinoma (Ductal Carcinoma in Situ; B5a)
    11.2.3 Invasive Carcinoma (B5b)
    11.3 Surgical Treatment of the Primary Lesion
    11.3.1 Oncologic Aspects
    11.3.2 Technical Aspects
    11.4 Lymph Node Surgery
    11.4.1 Procedure for Clinically Negative Node Status
    11.4.2 Procedure for Clinically Positive Nodal Status
    11.4.3 Procedure for Clinically Negative Node Status and Positive Sentinel Node
    11.5 Secondary Breast Reconstruction
    11.5.1 Timing the Reconstruction: Primary vs. Secondary Reconstruction
    11.5.2 Alloplastic Reconstruction (Implant Reconstruction)
    11.5.3 Autologous Reconstruction (Reconstruction Using Endogenous Tissue)
    11.5.4 Nipple Reconstruction
    Bibliography
    12 Medical Treatment of Breast Cancer
    12.1 Basic Principles and Objectives
    12.2 Adjuvant Drug Therapy
    12.2.1 Adjuvant Chemotherapy
    12.2.2 Neoadjuvant Therapy
    12.2.3 Adjuvant Endocrine Therapy
    12.2.4 Antibody Therapy
    12.3 Medical Treatment in Locoregional Recurrence
    12.4 Medical Treatment of Distant Metastases
    12.4.1 Endocrine Therapy in Premenopausal Patients with Distant Metastases
    12.4.2 Endocrine Therapy in Postmenopausal Patients with Distant Metastases
    12.5 Endocrine Maintenance Therapy after Completing Chemotherapy
    12.6 Chemotherapy of Metastatic Breast Cancer Combined with New Agents
    Bibliography
    13 Radiotherapy of Breast Cancer
    13.1 Adjuvant Radiotherapy after Breast-Conserving Surgery
    13.2 Adjuvant Radiotherapy after Mastectomy
    13.3 Effectiveness of Adjuvant Radiation Therapy: Prognostic Factors
    13.4 Integration of Adjuvant Radiotherapy into the Multimodal Treatment Concept
    13.5 Target Volume and Dose Concept
    13.5.1 Clinical Target Volume: Former Tumor Region, Mammary Gland, Chest Wall, and Regional Lymph Channels
    13.5.2 Partial Breast Irradiation
    13.5.3 Shortened Treatment Time: Alternative Fractionation Schemes
    13.6 Acute Side Effects and Complications of Adjuvant Radiation Therapy
    13.6.1 Acute Side Effects
    13.6.2 Late Complications of Radiation Therapy
    13.7 Planning and Implementing Radiation Therapy
    13.8 Radiotherapy in Primarily Inoperable Tumors, Recurrences, and Metastatic Disease
    13.9 Summary
    Bibliography
    14 Management of a Diagnostic Breast Center
    14.1 Expertise
    14.2 Equipment
    14.3 Facility Design
    14.3.1 Doctor’s Consultation Room
    14.3.2 Mammography and Sonography Rooms
    14.3.3 Breast MRI Room
    14.3.4 Rooms for a Second Ultrasound Unit and for Interventional Procedures
    14.3.5 Recovery Room
    14.4 Ambiance
    <

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